Hostname: page-component-848d4c4894-x5gtn Total loading time: 0 Render date: 2024-05-10T07:29:51.962Z Has data issue: false hasContentIssue false

Leptin: energy regulation and beyond to a hormone with pan-physiological function

Published online by Cambridge University Press:  28 February 2007

J. F. Andrews*
Affiliation:
Department of Physiology, Trinity College, Dublin 2, Republic ofIreland
*
Corresponding author: Dr J. Fred Andrews, fax +353 1 6793545, email jandrews@tcd.ie
Rights & Permissions [Opens in a new window]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Simposium on ‘Leptin: energy regulation and beyond’
Copyright
Copyright © The Nutrition Society 1998

References

Bennett, BD, Solar, GP, Yuan, JQ, Mathias, J, Thomas, GR & Matthews, W (1996) A role for leptin and its cognate receptor in haematopoiesis. Current Biology 6, 11701180.CrossRefGoogle Scholar
Blum, WF, Englaro, P, Ahtonasio, AM, Kiess, W & Ruscher, W (1998) Human and clinical perspectives on leptin. Proceedings of the Nutrition Society 57, 477485.CrossRefGoogle ScholarPubMed
Bornstein, RS, Uhlmann, K, Haldan, A, Ehrhart-Bomstein, M & Scherbaum, WA (1997) Evidence for a novel peripheral action of leptin as a metabolic signal to the adrenal gland. Diabetes 46, 12351238.CrossRefGoogle Scholar
Campfield, LA & Smith, FJ (1998) Overview: neurobiology of OB protein (leptin). Proceedings of the Nutrition Society 57, 429440.CrossRefGoogle ScholarPubMed
Cawthome, MA, Morton, NM, Pallett, AL, Liu, Y-L & Emilsson, V (1998) Peripheral metabolic actions of leptin. Proceedings of the Nutrition Society 57, 449453.CrossRefGoogle Scholar
Coleman, DL (1973) Effects of parabiosis of obese with diabetes and normal mice. Diabetdogia 9, 296298.Google ScholarPubMed
Coppack, SW, Pinkney, JH & Mohamed-Ali, V (1998) Leptin production in human adipose tissue. Proceedings of the Nutrition Society 57, 461470.CrossRefGoogle ScholarPubMed
De matteis, R, Dashtipour, K, Ognibene, A & Cinti, S (1998) Localization of leptin splice variants in mouse peripheral tissues by immunochemistry. Proceedings of the Nutrition Society 57, 441448.CrossRefGoogle Scholar
Farooqi, S, Rau, H, Whitehead, J & O'rahilly, S (1998) ob gene mutations and human obesity. Proceedings of the Nutrition Society 57, 471475.CrossRefGoogle ScholarPubMed
Hervey, G (1959) The effect of lesions in the hypothalamus in parabiotic rats. Journal of Physiology 145, 336352.CrossRefGoogle ScholarPubMed
Hoggard, N, Hunter, L, Trayhurn, P, Williams, LM & Mercer, JG (1998) Leptin and reproduction. Proceedings of the Nutrition Society 57, 421427.CrossRefGoogle ScholarPubMed
Kennedy, GC (1953) The role of depot fat in the hypothalamic control of food intake in the rat. Proceedings of the Royal Society B, 140, 578592.Google ScholarPubMed
Porter, RK & Andrews, JF (1998) Effects of leptin on mitochondrial proton leak and uncoupling proteins: implications for mammalian energy metabolism. Proceedings of the Nutrition Society 57, 455460.CrossRefGoogle ScholarPubMed
Trayhurn, P, Duncan, JS, Hoggard, N & Rayner, DV (1998) Regulation of leptin production: a dominant role for the sympathetic nervous system. Proceedings of the Nutrition Society 57, 413419.CrossRefGoogle ScholarPubMed
Weigle, DS (1994) Appetite and the regulation of body composition. FASEB Journal 8, 302310.CrossRefGoogle ScholarPubMed
Zhang, Y, Proenca, R, Maffei, M, Barone, M & Friedman, JM (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425432.CrossRefGoogle ScholarPubMed